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Welcome to the Greater Seymour Chamber of Commerce Seymour, Indiana is known as "The Crossroads of Southern Indiana" because it is conveniently located halfway between Illinois and Ohio on U.S. 50 and halfway between Indianapolis and Louisville, Kentucky on Interstate 65. Seymour is the home to two major industrial parks and a soon to open Certified Technology Park. We also offer a regional retail center with shopping centers, Shoppes of Seymour and a thriving downtown.
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